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In summary, evidence from pre-clinical and clinical studies reveal the consistent regulatory roles of androgens/AR in glucose and lipid metabolism, with clear sex-dependent differences ( Figure 1 )

The trailblazing EMPA-REG OUTCOME trial with empagliflozin in 2015 set the stage, demonstrating a 14% reduction in 3-point major adverse cardiovascular events (3P-MACE

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Translation : AOD 9604 attempts to directly stimulate fat breakdown at the cellular level (targeting the fat cell directly), while Tirzepatide changes your hunger signaling and improves how your body regulates glucose production