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Semaglutide may not be appropriate if you have: A personal/family history of medullary thyroid carcinoma (MTC) or MEN2 A history of pancreatitis or severe gastrointestinal disease Certain eye conditions (such as diabetic retinopathy), kidney issues, pregnancy, or a history of suicidal thoughts Always review risks, benefits, and alternatives with your healthcare provider before starting

These data indicate that semaglutide alone results in weight reduction involving both fat and lean mass loss, while adding -MSTN/-ActA to semaglutide results in similar weight reduction but with profoundly beneficial effects on body composition not only by preserving/increasing lean mass but also by markedly increasing fat loss

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CC is characterized by weight loss, primarily from muscle and body fat, resulting in muscle wasting 258