tobacco use risks Cigarette Smoking | Smoking and For People Who Smoke |

As far as bite being caused by casings or sauces, thats not likely

(1991): Tobacco addiction as a marker of age at onset of schizophrenia

The respiratory mucosa exists both in the nose and in the trachea and bronchi ( Cigarette smoke has been reported to induce inflammatory cell infiltration, especially of neutrophils, as well as cell division and mucus hypersecretion ( + lymphocytes, neutrophils, and eosinophils, suggesting that CSS exposure in the allergic condition could induce appreciable histological changes, although the dose and number of CSS administrations were insufficient to influence non-allergic mice

2) The course: Hard but fair