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3.4 Association between e-cigarette users and the prevalence of COPD The meta-analysis suggested a statistically significant association between current e-cigarette use and the increased prevalence of COPD, with a pooled OR of 2.03 (95% CI: 1.612.56), indicating a 103% higher prevalence compared to never-smokers, which is defined as lifelong smoking of less than 100 cigarettes or never participating in smoking or using any tobacco products, including e-cigarettes

Herbal cigarettes emit 12-22 mg of tar and 16-25 mg of CO per cigarette, comparable to a tobacco cigarette (Inhalation Toxicology, 2009)

Common side effects include: Increased heart rate and palpitations : Nicotine stimulates adrenaline release, which can make some individuals feel jittery or notice their heart pounding

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