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Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in down syndrome mouse models and in humans

determined by author and by software (PISA) Molecular Components in 10GS Label Count Molecule Proteins (2 molecules) A B 2 Glutathione S-transferase P1-1 (Gene symbol: GSTP1 ) Chemicals and Non-standard biopolymers (4 molecules) 1 2 L-gamma-glutamyl-S-benzyl-N-[(S)-carboxy(phenyl)methyl]-L-cysteinamide 2 2 2-(N-MORPHOLINO)-ETHANESULFONIC ACID * Click molecule labels to explore molecular sequence information

Such biochemical changes are direct or indirect effects of the mutation and primary cell loss, but could potentially contribute to the development of secondary neuropathologies and functional changes in the brain of Lurcher mice

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