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Chew On This: Facts About Oral Smokeless Tobacco in Singapore Oral smokeless tobacco products are products that can be chewed or sucked in the mouth

Tobacco control policies, such as smoke-free air policies and high prices for tobacco products, can decrease the smoking prevalence for youth and, in time, contribute to a lower adult smoking prevalence, thereby reducing health problems associated with smoking (Singh, et al., 2016)

The effect of smokeless tobacco consumption in oral microbiome composition was also investigated by identifying differentially abundant genera in oral buccal site of smokeless-tobacco-consuming and non-consuming healthy individuals

this leads to the inhibition of Gata6 promoter activity, loss of GATA6 protein, and subsequent loss of acinar differentiation and hyper-activation of oncogenic Kras (50)