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Smokers generally have a low body weight, but they have a higher amount of visceral fat - the type that accumulates around the organs and increases the risk of chronic disease They looked at whether people who had genes linked to smoking tended to have different body fat distributions to non-smokers

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This timing is based upon the half-life of nicotine (2 hours) and the observations that steady-state serum nicotine concentrations are achieved by this time of day in regular tobacco ST users (Benowitz et al., 1989)