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In two studies from Polosa and colleagues (2014a, 2016a), they identified retrospectively 18 mild to moderate asthmatic smokers who switched to e-cigarettes (either single or dual users)

By 1635, tobacco planting had moved away from Jamestown as settlers migrated to lands on the south side of the York River, and by 1648 the planters had received permission from Governor Sir William Berkeley to move north of the York River into the area that had become known as Northumberland

Its a story thats playing out across a bunch of different industries

While presumably less addictive, the reduced nicotine products still have similar health risks as regular cigarettes