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B12 needs vary based on the cause of deficiency, symptom severity, diet, and absorption issues (such as pernicious anemia or digestive conditions)
This article outlines an approach to interpreting and working up a high serum B12 in adults by separating four possibilities: intake-related elevation, disease-associated hypercobalaminemia (an elevated blood B12 associated with an underlying condition), analytical interference, and functional deficiency
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