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Despite noncombustible tobacco and nicotine without tobacco being less toxic than combustible tobacco, e-cigarettes (and other new nicotine delivery devices) cannot fulfill any promise they may have of harm reduction if we do not know what is in them, who is manufacturing them, and how they are marketed and advertised

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This review is important because there are no other comprehensive reviews of world literature on school-based smoking prevention programs, Julie McLellan, one of the authors of the review based at the Department of Primary Care Health Sciences at the University of Oxford in the United Kingdom, wrote in the journal