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Immune infiltrates in ectopic lesions include increased macrophages, mast cells, and memory CD4+ T cells, alongside decreased NK cells and plasma cells, mirroring autoimmune pathologies ( 2.2.4 Chronic inflammatory milieu Pro-inflammatory cytokines (TNF-, IL-6, IL-1, IL-8, IL-17) and chemokines (RANTES) accumulate in peritoneal and follicular fluid, creating a hostile microenvironment
This indicates that GSH is the main reductant responsible for maintaining the ER oxidoreductases in a reduced form, which is necessary for the reduction or isomerization of nonnative disulphide bonds
Inhibition of dendritic cell autophagy alleviates the progression of allergic rhinitis by inhibiting Th1/Th2/Th17 immune imbalance and inflammation
