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The RCT data could be analyzed as an observational study of consumption choices, which could provide a better estimate of the real effect of the NRT, but this is rarely done, and it would still be a very small observational study with one more source of potential confounding than naturally occurs (the effect of whether someone is inclined to comply with their assignment)
In addition, Australia has a minimum price for cigarettes, which is to prevent cheap cigarettes from being sold
Two people using the exact same product can experience hugely different nicotine exposures based simply on their personal smoking or vaping tendencies
[31] Health Concerns: Early awareness of the potential health risks associated with tobacco consumption emerged during the late 19th century
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