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Their analysispublished in the journal PLOS Genetics revealed that smoking could indeed influence appearance, in addition to other factors like lung health that are more well-recognized by scientific research

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However, this increased susceptibility is also likely due in part to the deleterious effects of cigarette smoke on the integrity of the respiratory epithelium, which provides easy entry for pathogens 45,46

"The industry said they weren't going to market to kids but that has never stopped them before so we were monitoring because we never know what to expect from them," said study author John Pierce, a professor of family and preventive medicine and the director of the Cancer Prevention and Control Program at the Moores Cancer Center at the University of California, San Diego