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Conclusions In light of new evidence about the etiopathogenic and pathophysiological mechanisms underlying NIHL, it becomes a priority to develop new therapeutic strategies that help to improve the quality of life of millions of people affected by this condition

Nine tendons and the median nerve must pass through this remarkably small space, explaining why even minor swelling causes significant problems

This ensures they are not only effective but also safe for use under recommended conditions

Second, and this is just as important, the cold environment itself creates a hostile setting for any potential microbial contaminants that might have been introduced