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The part of the brain that responds to rewards seems to be highly responsive during adolescence, which may lead adolescents to pursue the potential rewards available through smoking, Lydon-Staley said

In this study, examining the relationship of irritability being associated with smoking, indicated potential heterogeneity based on the Q-statistic results, though no outliers were observed in the leave-one-out test

Effects of long-term smoking The most common substances smoked are tobacco, marijuana, and cannabis

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