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Bibcode:2018PLoSO..1389015M
Consistent with the notion that structural alterations in these regions are a product of prolonged nicotine/tobacco exposure, group differences between smokers and nonsmokers within, for example, the insula were not detected among an adolescent/young adult participant sample with relatively lower exposure levels (0.9 0.7 pack-years on average) [85] but were observed among similarly aged individuals with relatively higher exposure levels (4.0 1.8 pack-years) [86]
The vast majority of both adult and child recipients were born in the United States 81.1% and 96.9%, respectively
The FDA stated that these products may offer potential harm reduction benefits for adult smokers, although the move has drawn criticism from public health advocates concerned about youth vaping
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