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30 Further youth-specific reasons are that e-cigarettes have appealing flavors, are easy to hide, are less expensive than traditional cigarettes, and do not smell like cigarettes

Dr Ed Stephens, senior research fellow at the University of St Andrews, said: This paper confirms the potential benefits of e-cigarettes and contributes to the growing body of evidence that the risk from chemicals in vapour is far lower than in cigarette smoke when an e-cigarette is used as the manufacturer intended. Jamie Hartmann-Boyce, senior health behaviours researcher at Oxford University and managing editor of the Cochrane Tobacco Addiction Group, said: We still need more studies on the long term safety of electronic cigarettes, but this study adds to the growing body of evidence suggesting electronic cigarettes are considerably safer than smoking regular cigarettes, as is using NRT long term

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89 Next to danger signals, pro-inflammatory cytokines and chemokines can additionally target the DC network and regulate their cellular activation status