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It has been suggested for smoking alternatives, such as electronic nicotine delivery systems (ENDS) and HTPs, that nicotine delivery and subjective effects such as satisfaction, liking and reductions in withdrawal symptoms are important factors, alongside their ability to replicate some of the ritualistic/sensorial cues associated with cigarette smoking, in determining their ability to facilitate smokers switching away from smoking 43,44,45,46,47,48

In the first trimester, it is usually because of an abnormality in fetal development, but later miscarriages may be a result of a health condition with the mother (x, x)

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