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Surgery Appeared More Complex Among patients who underwent surgery as first-line treatment, combined smokers had longer operative times, with a significant difference compared with tobacco-only smokers

Interestingly, the existence of harmful concentrations of diethylene glycol, a known cytotoxic agent, in e-liquid aerosols is contentious with some studies detecting its presence [4, 68, 70,71,72], and others finding low subtoxic concentrations [73, 74]

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This highly addictive chemical or substance has been the key reason why many smokers continue smoking despite the health risks that have been recently linked to cigarette smoking