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Nemmar et al., 2011)

If a patient is experiencing strong or frequent cravings, they may use a second piece within the hour Pharmacokinetics Both doses of Nicorette Gum demonstrated rapid onset in open-label, single-dose, crossover studies 1 Plasma concentration of nicotine over 12 hours after a dose of 2-mg Nicorette Gum vs

The restriction mirrors approaches taken in Finland and echoes EU discussions about flavour restrictions more broadly for tobacco and nicotine products