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CONCLUSIONS Our findings indicate that Singapores standardized packaging mandate is associated with positive quit-related outcomes, reduced attractiveness of tobacco products, brand distinction and the perceptions that some brands are less harmful, and increased effectiveness of graphic health warnings.

von Euler), Karolinska Institutet, Stockholm, showed that 4-methylnicotine exerted a very low pharmacological activity in all the tests used 1 while that of 6-methylnicotine was fairly strong The stimulating effect of 6-methylnicotine on the isolated guinea-pigs ileum was 25% stronger than that of natural nicotine