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Researchers emphasize that toxicology, longterm effects and appropriate dosing remain unknown in humans

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Serious Indicators of Vitamin B-12 Deficiency Severe vitamin B12 deficiency can cause signs and symptoms such as Yellow skin Weak muscles Numb or tingly hands or feet Trouble walking Severe joint pain Increasing shortness of breath Weight loss Irritability Lack of smell and taste sensations Memory loss Paranoia Delusions Deep depression What Does B12 Fatigue Feel Like

Many people are deficient without realizing it, especially with limited sun exposure, which can leave you feeling fatigued, low energy, or just off