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ACKNOWLEDGMENTS This work was supported by National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) R01 HL139239, NIH/NHLBI R01 HL139369, NIH/National Institute of Environmental Health Sciences (NIEHS) T32 ES007324, NIH/NIEHS T32 ES007126, NIH/NIEHS P30 ES000260, and NIH/NIEHS P30 ES010126