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However, with IBD-current biologic therapies, all these mean some patients primary non-responders, experience a loss of response, intolerance or side effects, defining the urgent unmet need for novel treatments (13, 14)

Increased expression of VEGF stimulates angiogenesis, acting on dopamine D1 receptors, and may cause, among other things, dyskinesia, a major side effect of L-DOPA, which may further reduce the quality of life of PD patients under L-DOPA medication (Veith and Henderson 2019) Increased VEGF expression has been also documented in astrocytes, endothelial cells (ECs), and monocytes of MS patients, potentially contributing to BBB permeability and the onset of MS

Taking more than the advanced dose rarely leads to faster or better results and significantly increases the risk of side effects (e.g., water retention, numbness, nausea)

Boost Endurance & Athletic Performance : L-Carnitine improves performance by increasing the body's reliance on fat for energy