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Therefore more than 300 million Americans, including 70 million children, live in states in which non-users of these products can be involuntarily exposed to either secondhand smoke from cigarettes and other smoked tobacco products or ENDS aerosol

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Importantly, these changes are further elevated in lung cancers or pre-cancers (abnormal cells or tissue that have the potential to develop into cancer), when compared to the normal lung tissue, supporting the idea that the epigenetic changes associated with smoking allow cells to grow more quickly