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Around 36.7% of adolescent males used to smoke tobacco products in Nepal in 2001 19

Further, the guidance states that NRT drug products that have demonstrated effectiveness for cessation or reduction in risk of relapse may include information in the labeling regarding how quitting smoking can lower a persons chances of having lung disease, heart disease, and the risk of getting certain types of cancer that are related to smoking, without providing additional data

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[75] Addiction is believed to be a disorder of experience-dependent brain plasticity