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Oxymetazoline has a more gradual onset, one review in the Journal for Drugs in Dermatology reported that the return of erythema is less common in patients using oxymetazoline as compared to brimonidine.5 Overtime, 10 to 20% of patients treated with commercially available brimonidine gel noted paradoxical erythema, this adverse effect was noted to be significantly less likely with the oxymetazoline topical treatment group, of which 1% of patients noted application site erythema as compared to 0.4% in the placebo group.7 Combination Therapy for the Management of Rosacea Oxymetazoline and brimonidine have demonstrated efficacy for the management of erythema associated with rosacea

When this tendon tears completely, deciding how to treat it can be challenging