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This suggests that orforglipron can serve as a "step-down" oral maintenance therapy after achieving target weight loss with more potent injectables

A mixed dietary fibre intake consisting of a combination of insoluble, soluble, and soluble viscous fibre from a variety of sources (e.g., cereals, fruit, vegetables and/or pulses) is recommended for cardio-metabolic health and to enhance digestive comfort [48,118,141]

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