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The expression of autophagy genes is increased in HepG2 ATP7B-KO and PHH WD cells To validate the copper-dependent gene regulation in HepG2 and HepG2 ATP7B-KO cells, both were cultured in RPMI medium, contrasting with the GSE107323 dataset, which used DMEM and RPMI medium, respectively

Despite this complexity, current treatments predominantly focus on BMI thresholds with little consideration for individual phenotypes or response variability (10, 11)

BNIP3, Bcl-2/adenovirus E1B 19 kDa-interacting protein 3,

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