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In the SURMOUNT-1 trial, participants on 10mg lost an average of 21.4% of their body weight over 72 weeks, approximately 49 pounds

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The compound's mechanism involves several physiological processes: Receptor Binding: Attaches to GHRH receptors on the pituitary gland Stimulation: Promotes endogenous GH production Feedback Regulation: Controlled by somatostatin for safety Gene Activation: Stimulates pituitary GH messenger RNA transcription A single sermorelin injection may increase GH levels for up to six hours, with repeated administrations maintaining elevated levels for up to two weeks

Preparation of insulin