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Studies on the changes of pharmacokinetics behaviors of phytochemicals and the influence on endogenous metabolites after the combination of Radix Bupleuri and Radix Paeoniae Alba based on multi-component pharmacokinetics and metabolomics

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We focused on the OGDHc-E2 given that the predominant effect of ABHD11 was on OGDHc activity, and we immunoprecipitated endogenous OGDHc-E2 from HeLa cells following treatment with ML226 for 6 h (Fig

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