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Key anti-myocarditis mechanisms include the upregulation of Th1-type cytokines, the elevation of Th2-type cytokines (IL-4 and IL-10), mitigation of oxidative stress, modulation of mitogen-activated protein kinase signaling pathways, and increased sarco-endoplasmic reticulum Ca2 + -ATPase levels (Javadi and Sahebkar, 2017)

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