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Glucagon receptor activation may partially counter this adaptation by increasing hepatic energy metabolism and possibly thermogenic pathways
Bone and muscle loss: The combination of reduced appetite and weight loss can lead to reduced muscle mass and bone density over time, especially when paired with inadequate protein intake and absence of strength training
Most studies reported the effects of dual GLP-1/glucagon (GCG) receptor agonists in NAFLD animal models
Funding This study was supported by a Commercial Development & Industry Partnership (CDIP) grant (CT20584-University of Sydney and Whiteley Corporation) and a Department of Industry, Innovation and Science (Innovative Manufacturing CRC Ltd.) and Whiteley Corporation co-funded project grant A Novel Approach to Biofilm Disruption and Removal (IMCRC/WLY/08052019.1)
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