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Symptoms of vitamin B12 deficiency or folate (folic acid) deficiency can include: Rapid breathing or shortness of breath Headaches Indigestion Loss of appetite Heart palpitations Vision problems Feeling weak or tired Diarrhea Tingling sensation A sore or red tongue, sometimes with mouth ulcers Problems with memory, understanding, and judgment (cognitive changes) If you have any of these symptoms, get in touch with a medical professional
Still, it suggested the mechanism was working in humans, not just mice
They also differ chemically, which matters at the bench: 5-Amino-1MQ is a permanently charged quaternary quinolinium salt, so molar calculations, solubility and analytical identity follow small-molecule rather than nucleotide or peptide conventions
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