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No overall differences in safety or effectiveness of ZEPBOUND have been observed between patients 65 years of age and older and younger adult patients
A baseline physical examination should include: Resting heart rate and blood pressure (sitting and standing) Cardiac auscultation to detect murmurs or irregular rhythms Assessment for signs of heart failure (peripheral edema, jugular venous distension) Baseline electrocardiogram (ECG) should be considered for patients with known cardiovascular disease, cardiac symptoms, or history of arrhythmias, rather than routinely for all patients over a certain age
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