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Standardized self-reported questionnaires were used for the following variables: alcohol consumption (none

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Table 1 Age-standardized mortality and YLDs rates across GBD regions and global in 1990 and 2021, and their temporal trends from 1990 to 2021 (based on GBD 2021 study data) Regional disparities in CVD attributable to smoking In 2021, East Asia had the highest number of deaths attributed to CVD, with 802131.94 deaths (Supplementary file Table 1)

[14] Systemic disease [edit] Aphthous-like ulceration may occur in association with several systemic disorders (see table)