Treatment groups The diabetic animals were randomly divided into seven groups comprising six animals in each group and one group of normal non diabetic animals received the vehicle 0.1 M citrate buffer pH 4.5
The ESI source conditions were set as following: sheath gas flow rate of 50 arbitrary units (Arb), auxiliary gas flow rate of 15 Arb, capillary temperature of 320 C, full MS resolution of 60,000, MS/MS resolution of 15,000, collision energy of 10/30/60 in normalized collision energy (NCE) mode, and spray voltage of 3.8 kV (positive) or 3.4 kV (negative)
Fatouros IG, Douroudos I, Panagoutsos S et al Effects of L-carnitine on oxidative stress responses in patients with renal disease
Routes of Administration Subcutaneous injection (standard): Lower abdomen (most common), love handles, or outer thigh