semaglutide loss of muscle mass impacts skeletal to a similar extent as caloric restriction in mice with diet‐induced obesity - Jeromson - The Journal Physiology Does Ozempic Cause Muscle Loss?

[16] [17] While the risk with GLP-1 receptor agonists appears lower, clinical trials and post-marketing surveillance of semaglutide have identified a small increased risk of gallbladder-related adverse events, including cholelithiasis and cholecystitis (gallbladder inflammation), compared to placebo

However, this study is limited by its small sample size and these results are not generalizable outside of veterans with GWI

For a heavy man with low-normal testosterone and no urgent fertility timeline, losing weight first is often the right move before reaching for hormones

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