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The SWI/SNF (BAF) complex, an ATP-dependent chromatin remodeling complex in the nucleus that endows DNA with the capacity for replication and enables selective gene expression and DNA repair and recombination, is frequently mutated in human cancers and thus exerts a great impact on tumorigenesis 51

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What combinatorial strategies (e.g., mitochondrial inhibitors plus immunotherapy) show the most promise in preclinical or early clinical studies for CRC