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Clinical studies of GLP-1 medications have shown average weight changes in the range of 10 to 20 percent over time, depending on the medication and patient profile
However, liraglutide exerted anti-inflammatory action by preventing the accumulation of C16 and C14 ceramide/sphingomyelin species and by affecting gut microbiota and prevented the initiation of fibrosis [26]
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Ethics approval All procedures followed were in accordance with the international standards of animal protection and the ethical principles of the National Council of Animal Experimentation and was approved by the Ethics Committee on Animal Use of the University Federal of Ouro Preto (#2014/17)
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