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The dual nature of Nrf2 activationprotective in normal tissues but potentially protective of tumor cells under certain conditionsdemands precise scheduling to maximize therapeutic synergy while minimizing potential interference with conventional treatments ( 6 Challenges and future perspectives Despite the compelling preclinical evidence and promising early clinical results, the full translation of SFNs potential into reliable clinical applications faces several significant challenges

The same principles apply regarding taking it before meals when possible

Excessively consuming high-nutrient diets, such as red meat, eggs, and fish, not only directly affects energy metabolism, but also regulates the composition of intestinal flora, leading to an increase in plasma TMAO concentration

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