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Chapters 1216 discuss the evidence that harm reduction strategies might impact the major diseases associated with tobacco and nicotine use

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Thus, real-time smoke formation studies have been reported using systems such as Fourier-transform infrared spectroscopy [16], quantum-cascade infrared laser spectroscopy [1720], dual infrared tuneable diode-laser systems [2124], gas chromatographymass spectrometry with a special puff-resolved trapping mechanism [2528], resonance-enhanced multiphoton ionisationtime of flight mass spectrometry (REMPI-TOFMS) and single-photon ionisationtime of flight mass spectrometry (SPI-TOFMS) [2936]

It can hardly be a recognition of the evidence concerning the connection between cigarette smoking and disease which has prompted the tobacco companies to increase the amount of filter material in cigarettes, because it is impossible to find an executive of any tobacco company who will admit that cigarette smoking has the slightest causal relationship to lung cancer and other maladies