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Although the total concentrations (oxidized plus reduced forms) of NAD(H) and NADP(H) in the RBC are similar (~25 mol/L), the cell maintains these two redox systems with similar redox potentials at such different set-points in the same cell by isolating their metabolism through the specificity of cytoplasmic dehydrogenases

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Additional mechanisms include collagen and elastin synthesis stimulation in the scalp dermis, anti-inflammatory effects that reduce the cytokine environment hostile to follicle function, and a proposed counteraction of the effects of dihydrotestosterone (DHT, the androgen primarily responsible for follicle miniaturization in androgenetic alopecia), though the DHT-related mechanism is less clearly characterized than the others

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