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In vitro , in comparison with control, healthy animals, the assessment of splenic cells (day 21) demonstrated that the 6-methylprednisolone animals had declined reactivity to nitrogen, while the addition of BPC 157 (1 g/g cream) returned cell reactivity to normal values (Mikus et al., 2001

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While clinical development for obesity was discontinued in 2007 after a Phase IIb trial failed to achieve its primary endpoint, the peptide remains a valuable research tool for investigating adipose tissue biology, lipolytic pathways, and receptor-independent signaling mechanisms