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Shortly after the shortage ended, a compounding trade group called the Outsourcing Facilities Association filed a lawsuit in a Texas federal court against the FDA, claiming that tirzepatide remains in short supply and that the decision to officially end the shortage is abruptly depriving patients of a much-needed treatment and artificially raising drug prices. Some telehealth companies selling compounded tirzepatide have introduced versions of the medication with other ingredients, including glycine, niacinamide, and other B vitamins

1a,b), the DPP-4 resistant GLP-1 analogue was cleaved after positions G2, S12 and W25 (Supplementary Fig

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