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An analog of taurocholic acid, tauroursodeoxycholic acid (TUDCA), is a naturally occurring bile acid and is a conjugate of taurine and ursodeoxycholic acid (UDCA)
Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)
Side Effects: Generally well tolerated in research settings
The most evidence-informed combinations: SS-31 + NAD+ (the mitochondrial energy stack addresses both coenzyme depletion and membrane structural function)
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