PMID: 21875351): The study showed randomized double blind placebo controlled RCT in 40 healthy adults showing no significant changes in oxidative stress biomarkers or RBC glutathione after 4 weeks of 500 mg twice daily oral GSH Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function , published in European Journal of Clinical Nutrition (Sinha R et al., 2018
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76 Additionally, excessive GSH may alter bacterial intracellular redox homeostasis, which paradoxically leads to increased production of ROS and causes oxidative damage