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Early dose jumps also dehydrate you faster than gradual increases because severe appetite suppression reduces fluid intake alongside food consumption, and dehydration independently stresses pancreatic function

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Some people may notice positive changes in their appetite, such as reduced cravings or feeling more satisfied between meals, within a few weeks, but the most significant results are likely to happen when you reach the maintenance dose from around week 13 of treatment

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Calibration Test your thermometer in ice water (should read 32 degrees Fahrenheit / 0 degrees Celsius) to verify accuracy

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