glp-1 liver toxicity The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis glp-1 liver toxicity The future

Since mitochondrial metabolism is prevalent in normal high-energy-demand tissues, such as the heart and liver, OXPHOS inhibitors (e.g., IACS-010759) have shown dose-limiting toxicities (DLT) in some clinical trials, hindering their widespread application [173]

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and reconstitution guidance that implies human administration rather than laboratory use

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