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However, long-term treatment with vitamin E has been associated with increases in all-cause mortality and the risk for prostate cancer [25,26,27], suggesting the need to evaluate the efficacy and safety of this agent

Fibroids arent always symptomatic, but can result in chronic pain, abnormal bleeding, scarring, reduced fertility, and lower quality of life for women

Nevertheless, several follow-up studies have reaffirmed DHODHs ferroptosissuppressive function under specific metabolic or oxidativestress conditions 93,94,95,96 , supporting the notion of a contextdependent mechanism rather than a universally essential role

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